WebFeb 28, 2024 · One of the main problems in chemotherapy using platinum drugs as anticancer agents is the resistance phenomenon. Synthesizing and evaluating valid alternative compounds is challenging. This review focuses on the last two years of progress in the studies of platinum (II)- and platinum (IV)-based anticancer complexes. In … WebEpithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related death. The high mortality and morbidity associated with EOC are mostly due to late diagnosis and chemotherapy drug resistance. Currently, the standard first-line chemotherapy regimen is systemic administration of platinum-based chemotherapy combined with a taxane. A …
Cisplatin-Membrane Interactions and Their Influence on …
WebJun 1, 2024 · The charge convertibility of UPD was confirmed by zeta potential changes at tumor extracellular pH = 6.5 and normal physiological pH = 7.4 (Fig. 4A). At pH = 6.5, … WebPatients receiving cisplatin were more likely to be alive at 1, 2 and 3 years. Median survival for mitomycin and cisplatin was 10.8 and 40.8 months, respectively. Median disease-free survival and progressionfree survival were 10.3 and 9.1 mont- hs, respectively. A multicenter registry evaluated CRS combined with HIPEC for diffuse, malignant, PM. farm style throw pillows in navy and ivory
Cisplatin 5. The Role of Platinum Electrodes - Chemistry LibreTexts
WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in … WebMaterial and Methods: Chitosan, cisplatin, curcumin, Lipoid S75 were selected as structural components and ionic gelation method was used for preparation of LPHNPs. Nanoparticles were formed via ionic interaction of positively charged chitosan and negatively charged lipid. Results: The optimized nanoparticles were of 225 nm with cationic charge ... WebJan 11, 2024 · Cisplatin has a small size and no net charge and thus it is expected to enter via passive diffusion, even if low due to its hydrophilic nature. Indeed, studies in model … farm style twin bed