WebAug 21, 2007 · Using CTLA-4-deficient mice expressing CD28 molecules with various point mutations in the CD28 cytosolic tail, the present study documents that in vivo costimulation for induction of autoimmune disease strictly requires an intact C-terminal proline motif that promotes lymphocyte-specific protein tyrosine kinase Lck binding to the CD28 cytosolic ... Webcytosolic: ( sī'tō-sol'ik ), Relating to or contained in the cytosol.
Mutation of a tyrosine localization signal in the cytosolic tail of ...
Web使用Reverso Context: It inhibits cytosolic PHOSPHOLIPASE A2, and displays anticoagulant activity.，在英语-中文情境中翻译"CYTOSOLIC" 翻译 Context 拼写检查 同 … WebNov 22, 2010 · The cytosolic 518-Ynd1 mutant was expressed at relatively low levels, but could still be efficiently coimmunoprecipitated with E4orf4. Only very low non-specific binding of Ynd1 to the E4orf4-specific antibodies was observed in the absence of E4orf4. Thus, the Ynd1 cytosolic tail can associate specifically with E4orf4. how to save reddit gifs on iphone
cytological - 英中 – Linguee词典
Webthe cytosolic tail of class I heavy chains in their dislocation, a deletion of all but four amino acids of the cytosolic domain of HLA-A2 was generated (Fig. 1). The remaining four residues were retained to allow the class I heavy chain to properly insert in the membrane (21). Others have shown that similarly WebMay 1, 2005 · Subunit interactions alone can mediate synaptic localization as endogenous GLR-1, or GLR-2 subunits can rescue the localization defects of subunits lacking tail sequences. Moreover, GLR-2 cytosolic tail sequences are sufficient to confer synaptic localization on a heterologous reporter containing a single-transmembrane domain. Web2. active Eph receptor activates a cytoplasmic tyrosine kinase that phosphorylates ephexin, a Rho GEF bound to the tyrosine on cytosolic tail, 3.ephexin to activate the Rho protein RhoA 4. Rho A-GTP regulates various downstream target proteins, including some effector proteins that control the actin cytoskeleton north face ultra pack