Desmethylepipodophyllotoxin
Web4'-Demethylepipodophyllotoxin(4'-DMEP) is a key intermediate compound for the preparation of podophyllotoxin-type anti-cancer drugs; a potent inhibitor of microtubule … WebPodophyllotoxin is the natural product precursor of the chemotherapeutic etoposide, yet only part of its biosynthetic pathway is known. We used transcriptome mining in Podophyllum …
Desmethylepipodophyllotoxin
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Web摘要： We have analyzed 1 kb of cloned human c-fos sequence (-711 to +287) for calf thymus DNA topoisomerase II cleavage sites in vitro. Using the anti-tumor drug VP16 (demethylepipodophyllotoxin-beta-D-glucoside) with purified … WebThe preparation of 4'-demethylepipodophyllotoxin II is known and is usually carried out by demethylation of podophyllotoxin I by HBr, according to the original method described …
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WebThe 4- O -β-d-glucopyranoside of DMEP ((-)-4'-desmethylepipodophyllotoxin) (GDMEP), a natural product from Podophyllum hexandrum , is the direct precursor to the … Web4'-Demethylepipodophyllotoxin C21H20O8 - PubChem Apologies, we are having some trouble retrieving data from our servers... PUGVIEW FETCH ERROR: 403 Forbidden …
Web4'-O-Desmethyl-1-O-methylepipodophyllotoxin Catalogue No.: PA 05 70100 CAS : 118356-05-1 Molecular Formula : C22H22O8 Molecular Weight : 414.41 Enquire Details Etoposide - Impurity K di-4'-O-Desmethylepipodophyllotoxin Catalogue No.: PA 05 70110 CAS : NA Molecular Formula : C42H38O15 Molecular Weight : 782.75
WebNov 2, 2006 · A series of new 4β-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives were synthesized and evaluated, together with some previously prepared ones, for their … simple drawing of a planeWeb氟吗啉 标准品由上海铭博生物科技有限公司提供！我司本着标准*、质量*、服务*、信誉*的宗旨，为客户提供轻松便捷，安全 ... simple drawing of a puppy for kidsWeb2024年在全县科级干部廉政集体谈话会上的讲话下面是我为大家整理的在全县科级干部廉政集体谈话会上的讲话,供大家参考. 在全县科级干部廉政集体谈话会上的讲话 同志们: 今天,县委决定把全县科技干部同志召集起来,进行廉政集体谈话,非常重要.刚才,文库网_wenkunet.com simple drawing of an animal cellWebSep 11, 2015 · (–)-4′-Desmethylepipodophyllotoxin is the direct precursor to etoposide, which currently is made by chemical modification of podophyllotoxin. Potent topoisomerase activity of etoposide was discovered by serendipitous derivatization of trace amounts of … raw gold price per gramWebWe have analyzed 1 kb of cloned human c-fos sequence (-711 to +287) for calf thymus DNA topoisomerase II cleavage sites in vitro. Using the anti-tumor drug VP16 (demethylepipodophyllotoxin-beta-D-glucoside) with purified topoisomerase II, we identify twelve sites. Five sites are clustered around pos … simple drawing of a plant cellWebNov 2, 2006 · A series of new 4β-5-Fu-substituted 4'-demethylepipodophyllotoxin derivatives were synthesized and evaluated, together with some previously prepared ones, for their cytotoxic activities against four tumor cell lines (HL60, P388, A549 and BEL7402). Three of these compounds exhibited superior in vitro anticancer activity against P388 and A549 … raw gold picturesWebAug 7, 2024 · C4 variation of 4'- O -demethyl-epipodophyllotoxin (DMEP) is an effective approach to optimize the antitumor spectra of this compound class. Accordingly, two … raw gold sellers