WebJan 6, 2024 · Activation of PERK leads to phosphorylation of the eukaryotic initiation factor 2α (eIF2α), which is a critical regulator of protein translation. Phosphorylated eIF2α prompts a dramatic reduction in protein translation to limit cellular amino acid consumption. Web(3398) Phospho-eIF2α (Ser51) (D9G8) XP® Rabbit mAb Supplier Cell Signaling Technology. Host Rabbit Type Primary Clonality Recombinant (D9G8C8D5) Recombinant Yes Conjugate Unconjugated Target Eukaryotic translation initiation factor 2 subunit 1 (Human) UniProt P05198 - IF2A_HUMAN. Gene
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WebPhospho-eIF2α (Ser51) (D9G8) XP ® Rabbit mAb (Biotinylated) detects endogenous eIF2α protein only when phosphorylated at Ser51. This antibody does not recognize elF2α … Web(3398) Phospho-eIF2α (Ser51) (D9G8) XP® Rabbit mAb - Cell Signaling Technology - CiteAb 726 citations – A rabbit monoclonal antibody, raised against Eukaryotic translation … cities skylines change time of day
Phosphorylation of eukaryotic initiation factor-2α (eIF2α …
WebMay 3, 2024 · Stress-responsive kinases phosphorylate eIF2α at conserved Ser51, transforming eIF2 from substrate into a competitive GEF inhibitor. ... yet eIF2Bα deletion impairs phospho-inhibition of eIF2B, consistent with the subunit’s role in binding eIF2α-P. Point mutations with identical phenotypes cluster at the interface between eIF2Bα and ... Web5199 Phospho-eIF2α (Ser51) (D9G8) XPÒ Rabbit mAb (Biotinylated) 2.2. Kennzeichnungselemente Ergänzende Gefahrenmerkmale EUH210 - Sicherheitsdatenblatt auf Anfrage erhältlich 2.3. Sonstige Gefahren Kann allergische Reaktionen hervorrufen. Den vollen Wortlaut der H-Sätze und EUH-Sätze in diesem Abschnitt finden Sie in Abschnitt 16 Phospho-eIF2α (Ser51) (D9G8) XP ® Rabbit mAb detects endogenous eIF2α only when phosphorylated at Ser51. The antibody does not recognize elF2α phosphorylated at other sites. Human eIF2alpha residue Ser52 historically has been referenced as Ser51. Species Reactivity: Human, Mouse, Rat, Monkey, D. melanogaster cities skylines chirper mod